Salivary Alpha-Amylase Alteration as a Possible Indicator for Diabetes
نویسندگان
چکیده
Diabetes mellitus has been documented to be associated with alterations in salivary composition and function. Therefore, the main aim of this case-control study was to determine the alterations of salivary alpha-amylase in diabetics compared to healthy people. A total of 40 type 2 diabetic subjects (15 male/ 25 female, aged from 4270 years, mean age 55.6 ±7.11) were selected. Also, the control group consisted of 40 clinically health people (20 male/ 20 female, aged from 49-70, mean age 56.08 ±8.8).Salivary alpha-amylase, salivary flow rate and DMFT index were evaluated in these two groups. Data were analyzed using Chi-square test and t-test. There were significant differences in salivary alpha-amylase level, salivary flow rate and DMFT index between diabetic patients and control group. Salivary level of alphaamylase is significantly higher in diabetics compared to healthy people. Our results in consistent with the literature propose an idea regarding the possible role of salivary alphaamylase as a diagnostic aid.
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